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Before the interview, Dr. Chris Ahern and the Brain Matters team talked about reproducibility in science and how predictions and results do not always align.

“Don’t feel too pigeon-holed to get a result… If predictions don’t work out, that’s okay! That’s the data.”

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  • 3 years ago
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When Brain Matters sat down with Dr. Alyssa Brewer from The University of California, Irvine, we talked about maps of visual information in the brain.

The visual cortex is the area of the brain that is responsible for processing visual information. Much of this brain area is organized into maps where each hemisphere encodes information about half of the visual field. Light seen through the fovea (an area of the retina used for fine visual acuity) occupies a large amount of space in the cortical representation of the visual field.

Find the full review article on PubMed.

Image Credit:
Brian A. Wandell, Serge O. Dumoulin, Alyssa A. Brewer, Visual Field Maps in Human Cortex, Neuron, Volume 56, Issue 2, 25 October 2007, Pages 366-383.

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  • 3 years ago
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Historical and current perspective on tobacco use and nicotine addiction

When Dr. John Dani came to talk with us about nicotine addiction, he mentioned a letter Nobel Prize winner Sir Henry Dale wrote to a colleague. In a review Dani wrote on the history of nicotine addiction, he referenced the letter:

The excitement, energy and progress seem unique to our time, but our impressions were expressed well by Henry Dale more than 50 years ago. Dale, who identified ACh, when in his eighties, wrote to his friend Thomas R. Elliott, who also had made seminal contributions toward understanding synaptic transmission. An excerpt from Dale’s 1958 letter expresses the dizzying rate of scientific advances he observed when visiting Bernard Katz’s lab while Katz was in his astonishing prime:

‘I feel almost bewildered by the kind of detail which such people are now elucidating with the aid of electron-ultramicroscopy, and also with an electrical recording which they can now achieve of the transmitted excitatory process at the motor end-plate of a single muscle fibre…I find it really exciting to think of the contrast between physiology as we had it from Langley and Gaskell, and what it is becoming today. A great deal indeed has happened since you first suggested a chemical mechanism for the transmission of the excitatory process from a nerve ending; and it goes on happening with a constant acceleration.’ (Letter from Dale to Elliott, 29 June 1958, Royal Society Archives, quoted by Tansey).

Read the full article here: http://www.sciencedirect.com/science/article/pii/S0166223611000725#

John A. Dani, David J.K. Balfour, Historical and current perspective on tobacco use and nicotine addiction, Trends in Neurosciences, Volume 34, Issue 7, July 2011, Pages 383-392.

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  • 3 years ago
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Our first episode of Ripple Recaps has premiered! On this bonus episode, Brian talks about Artificial Fear Memories.

Listen on iTunes

References:

  1. Creating a False Memory in the Hippocampus
    Ramirez et al. (2013)
    https://www.sciencemag.org/content/341/6144/387
  2. Generation of a Synthetic Memory Trace
    Garner et al. (2012)
    http://www.sciencemag.org/content/335/6075/1513
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  • 3 years ago
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Brain Matters is a podcast where real neuroscientists sit down and talk about the brain. Sit in on conversations between scientists you've never had the chance to hear before.
Brain Matters is produced by neuroscience graduate students at The University of Texas at Austin.

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